UK watchdog criticizes Moderna for Covid-19 trial's use of WhatsApp to dangle...
The UK’s pharma marketing watchdog, the Prescription Medicines Code of Practice Authority, is taking issue with the way Moderna allegedly sought to increase participation in a Covid-19 vaccine trial...
View ArticleJ&J folds cardiovascular and metabolic drug unit
Johnson & Johnson is winding down its pharma division’s cardiovascular and metabolic unit, Endpoints News has learned. The decision primarily impacts the sales, marketing and medical affairs teams,...
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Pfizer pulls sickle cell drug from all markets after data review showed rise...
Pfizer said it will withdraw its sickle cell disease treatment Oxbryta from all markets worldwide, after data showed an “imbalance” of fatalities and complications common to the disease. The surprise...
View ArticleNext-gen obesity biotech BioAge Labs to raise $198M in IPO
A California biotech that began as an anti-aging company, then licensed an Amgen heart failure drug for $1 million upfront and repurposed it as a weight loss therapy, has lined up a $198 million IPO....
View ArticleBarcelona VC firm Asabys raises second fund, adding to Europe’s biotech...
Asabys Partners said Thursday it closed its second health innovation fund at €180 million, or about $200 million. The Barcelona-based VC firm’s raise expands the money available to biotech and health...
View ArticleAGC Biologics to lay off 95 workers; Vertex taps Lonza to manufacture Casgevy
Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. AGC Biologics said it is laying off a total of 95 staffers, which...
View ArticleUpdated: FDA adcomm votes to limit Opdivo, Keytruda use in stomach,...
The FDA’s Oncologic Drugs Advisory Committee on Thursday voted 10-2 with one abstention that Merck’s Keytruda and Bristol Myers Squibb’s Opdivo are not beneficial as a first-line treatment for stomach...
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Genentech's blood cancer drug Gazyva moves toward more indications in immunology
Genentech plans to expand the label for its CD20-targeting antibody Gazyva following positive late-stage data in an autoimmune disease that impacts the kidneys. In the Phase 3 REGENCY study, a higher...
View ArticleInsilico Medicine, an early force in AI-driven drug R&D, lets IPO plans peter...
One of the original AI-driven drug discovery and development biotechs has let its plans to list on the Hong Kong stock exchange lapse for the second time in as many years. Insilico Medicine, a...
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AstraZeneca's lung cancer blockbuster Tagrisso wins label expansion in...
AstraZeneca’s blockbuster lung cancer treatment Tagrisso scored a new FDA approval on Thursday in certain EGFR-mutated early-stage patients whose non-small cell lung cancer has not spread, but can’t be...
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FDA lifts hold on Biomea’s diabetes trials
The FDA lifted a clinical hold on two trials testing Biomea Fusion’s diabetes treatment. The news, announced Thursday, sent the company’s shares $BMEA up by about 4% to $9.11, inching closer to its...
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FDA approves Bristol Myers and Karuna's schizophrenia drug, in milestone for...
The FDA on Thursday approved Bristol Myers Squibb’s new schizophrenia drug in one of the year’s most anticipated regulatory decisions. The approval gives Bristol Myers a significant foothold in the...
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Endpoints 11 winner Seaport Therapeutics: The Karuna team is back with...
↑ CEO Daphne Zohar Total raised $100 million Headquarters Boston, MA On Thursday, members of Seaport Therapeutics’ founding team watched from afar as their old company, Karuna Therapeutics, got its...
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Endpoints 11 winner Capstan Therapeutics: Trying to win the in vivo CAR-T race
↑ CEO Laura Shawver Total raised $340 million Headquarters San Diego, CA Turning a patient’s own cells into powerful disease combatants — without the complexity of removing them from the body to do so...
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Endpoints 11 winner Mirador Therapeutics: Applying precision medicine to...
↑ CEO Mark McKenna Total raised $400 million Headquarters San Diego, CA 2024 is on track to be a record-breaking year for venture capital funding of immunology-focused biotech startups. And Mirador...
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Endpoints 11 winner Formation Bio: A Silicon Valley-fueled unicorn aiming to...
↑ CEO Benjamine Liu Total raised More than $600 million Headquarters New York, NY During his doctorate work at the University of Oxford, Benjamine Liu came across what he thought were some promising...
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Endpoints 11 winner Xaira Therapeutics: Biotech’s largest AI bet with A-list...
↑ CEO Marc Tessier-Lavigne Total raised More than $1 billion in committed capital Headquarters South San Francisco, CA David Baker’s Seattle laboratory has become the place for the biopharma industry...
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Endpoints 11 winner Metsera: Clive Meanwell wagers on obesity after Medicines...
↑ CEO Clive Meanwell Total raised $290 million Headquarters New York, NY Shortly after Clive Meanwell sold The Medicines Company to Novartis for nearly $10 billion in 2020, he started a life sciences...
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Endpoints 11 winner Ascidian Therapeutics: A search-and-replace technology...
↑ CEO Michael Ehlers Total raised $90 million Headquarters Boston, MA Ascidian Therapeutics has a secret list of nearly 400 diseases that its gene-altering technology might help cure. But you’ll only...
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Endpoints 11 winner Cardurion Pharmaceuticals: A shot at one of heart...
↑ CEO Peter Lawrence Total raised More than $500 million Headquarters Burlington, MA ‘Undruggable’ targets aren’t just in oncology. Cardurion Pharmaceuticals is hoping to become the first to...
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